This article is an overview of the diagnosis and management of aHUS in the emergency care setting. aHUS is a life-threatening disorder in which microvascular thrombosis affects the kidneys, brain and/or other organs. Its clinical and laboratory features overlap with those of other thrombotic microangiopathy (TMA) disorders including STEC-HUS and TTP. Distinct treatment strategies are used in each case, but the critical first step involves recognition of a TMA, based on the presence of microangiopathic haemolytic anaemia and thrombocytopenia.
Independent expert commentary provided by Dr Tom Barbour, PhD FRACP whois a nephrologist at The Royal
Melbourne Hospital (RMH), Victoria.
Please login below to download this issue (PDF)